Hepatic amyloidosis

Hepatic amyloidosis is a rare disease that presents as an infiltrative disease involving liver. Amyloidosis is a systemic disease characterized by the extracellular deposition of amyloid protein in many organs. Progressive organ involvement leads to organ malfunction and death usually resulting from renal and/or cardiac involvement. Liver and spleen are major sites of involvement. The wide range of presenting symptoms encountered makes rapid clinical diagnosis difficult. None of the present imaging techniques is capable of specifically demonstrating the presence of amyloid. Even when suspected clinically and radiologically, the diagnosis of amyloidosis depends on a tissue biopsy to confirm the presence of amyloid deposits. To provide more detailed understanding of hepatic amyloidosis, here a case of amyloidosis involving liver is presented with radiological imaging findings including computed tomography (CT).